Department of Signals and Systems, Chalmers University
of Technology, Göteborg
Address: Department of Signals
and Systems, Chalmers University
of Technology, SE-412 96 Göteborg, Sweden Visiting Address: Johanneberg Campus, E-bulding,
Hörsalsvägen 9–11, 5th floor Web page:http://www.chalmers.se/s2/EN/
Contact person: Professor Mikael Persson,
Division Head, Biomedical Engineering, phone: +46 (0)31 772 1576
Within the department, the so-called Image Analysis Group carries out research in the field of imaging
and image analysis, especially bioimaging and biomedical image
processing, analysis and modeling. This includes the analysis of
spatio-temporal ultrasonic image sequences for cardiovascular research
and light- electron- and fluoroscence microscopy images for neuroscience
research. The group is also developing advanced image analysis
and laser diagnostic procedures for combustion research. The Image
Analysis Group is collaborating intensively with research teams
at the Medical Faculty, Göteborg University and with the Depts
of Mathematics and Physics, Chalmers University of Technology.
International collaboration includes Cambridge University, Imperial
College in London, Toronto University, New York University, Ecole
Nationale Supérieure des Télécommunications
in Paris, Johns Hopkins Medical School in Baltimore and Wake Forest
Medical School in Winston Salem.
Research connected to South Asia
November 2005 Prof. Tomas
Gustavsson (who has since left Chalmers) and his
research group received SEK 1 million as a two-years grant (2006-07)
project coordinator) from Sida's Developing Country Research
Council for a project titled ”Computer-aided
oral cancer screening and education in India”. More
information about the Sida grants 2005.
The project aims at
creating new technological devices to discover oral cancer in an
early stage, in collaboration with dentists. The key person
in the project is Dr. Artur
Chodorowski, who has developed the equipment being used for
oral screening (which was also the issue for his doctoral dissertation,
defended in the year 2000).
Another member affiliated to the Dept. of of Signals and Systems is Shantanu Padhi (photo to the left).
Prof. Gustavsson, Dr. Chodorowski, and Dr. Padhi all participated in a meeting with Lars Eklund and Sidsel Hansson from SASNET, held at Chalmers on Friday 18 April 2008. More information about the meeting.
In 2003 the research group was approached
by Prof. Chitta Choudhury, working at the Institute
of Health and Community Studies at Bournemouth University,
UK, and also at the A.B. Shetty
Memorial Institute of Dental Sciences (ABSMIDS),
in Mangalore, India (photo to the right). Prof. Choudhury
got interested in the research at Chalmers, as oral cancer is very
common in India, 30 % of all cancer patients suffer from oral cancer.
One explanation for this is said to be the wide-spread use of chewing
pan/betel nuts in India.
The project includes that the Swedish researchers go to Mangalore
and install the screening equipment with computers and cameras, and
teach dentists and dental assistants to handle the new technology. More
information about the project (in Swedish).
The objectives of the project are to:
• Implement and adapt to Asian developing countries a computer-aided analysis
and decision support system for the early detection and diagnosis of malignant
and pre-cancerous oral lesions;
• Develop a cost-effective screening and education module for prevention
and control of oral cancer in India; and
• Implement a national pilot survey in India aiming at developing a model
for cost-effective screening and education program for South and Southeast Asian
• The project will assist in developing
a cost-effective screening technique for the program of oral pre-cancer
prevention and control in India
• It will
be considered a powerful evidential
adjunct to support motivational program for quitting of personal
habits among millions in India and regional countries.
diagnosis and screening will get accreditation from international
learned organizations like WHO, if the project is extended to the
The proposed diagnostic system is based on inexpensive
registration technique, which means that it can be easily adopted
by developing countries.
Clinicians will benefit from digital
image analysis tools for objective digital measurements on patient
The project will strengthen the (Indian) national
Oral Health System, in accordance with WHO recommendations
and United Nations‚ millennium
health-related goals. (Mexico City, Nov 2004,
In August 2008, Dr. Artur Chodorowski received a SASNET planning grant for a project titled ”Pattern Recognition methods for early detection of precancerous oral lesions in South Asia”. The planning grant will be used to extend a previous SIDA project run during 2006 and 2007. The extension consists of including histological image data into the diagnostic system and
establishing a new collaboration with additional South Asian researchers and institutions. More information about the 2008 SASNET planning grants. Project abstract: The objective is to develop a computer-aided diagnosis system for detection of potentially precancerous
oral lesions. The input data will primary consist of true color and multi-spectral images of oral cavity,
combined with histological images of suspicious tissues and possibly molecular investigations. The data
will be collected in a database over commonly prevailing oral lesions, and will serve for inferring reliable
decision and classification rules. The system will support the practicing oral experts and dentists with an
additional opinion statistically derived from the collected data. The Indian side stands for data collection
and histological investigations, and the Swedish side contributes with signal analysis and machine
learning methods. The South Asia, and in particular India, suffer most from the oral cancer in the word,
and the system will hopefully contribute to early detection of precancerous lesions and decrease the oral
cancer mortality rates.