Division of Pharmacognosy, Department of Medicinal Chemistry, Uppsala
Postal address: Inst. f. Läkemedelskemi, Avd.
f. Farmakognosi, BMC (Uppsala Biomedicinska Centrum),
Box 574, SE-751 23 Uppsala Visiting address: Husargatan 3, Entrance C7, Offices B7:5, Laboratories
B5:3 Fax: +46(0)18 50 91 01 Web page:http://fkogserver.bmc.uu.se/
Contact person: Professor Lars
Bohlin, Head of department; phone: +46 (0)18 471 4492
Research and education connected to South Asia:
The Division of Pharmacognosy at the Dept of Medicinal Chemistry
(Läkemedelskemi) has for many years been connected to South Asia,
especially Sri Lanka. Assistant professor Premila
Perera Ivarsson, an expert on
Ayurvedic medicine, dealt with traditional medicine in her research; a
task which included identifying anti-inflammatory components from Sri
Lankan medicinal plants and herbal drugs. She was also teaching the 5
credits course on Global Pharmacy at Uppsala University, and responsible
for sending Swedish students to Sri Lanka as part of the Linnaeus Palme
Premila Perera Ivarsson however tragically passed away on 19 June, 2002,
and her funeral was held in the Uppsala Cathedral on July, 8, 2002.
The connection to Sri Lanka remains however. Professor Lars
Bohlin is currently engaged in a research collaboration with
University of Colombo, Sri Lanka.
They work jointly in the
field of biochemistry of medicinal plants.
Prof. Bohlin also teaches at the
course in Global Pharmacy, organised by the Division every
year, and Prof. Welehinda supervises students from
the course when they do field work in Sri Lanka.
Pathmasiri has been engaged in research on Medicinal Plants
and herbal preparations in Sri Lanka. He defended his Licentiate thesis
2 Inhibitors of Natural origin: Dereplication, Isolation, and Structure
at the department on 3 November 2003. Abstract of the licentiate thesis:
Cyclooxygenase-2 (COX-2) enzyme, also known as prostaglandin endoperoxide
H synthase-2 (PGHS-2), is shown to be involved in inflammation and cancer;
thus it has become a drug target for finding novel anti-inflammatory drugs.
Two Sri Lankan medicinal plants, Gynandropsis gynandra (Capparidaceae)
and Acronychia pedunculata (Rutaceae), were selected for investigation
of novel COX-2 inhibitors, based on their use in traditional medicine
against inflammatory diseases.
Wimal Pathmasiri has since moved from the department, and defended his doctoral dissertation in 2007 at the Dept. of Biochemistry & Organic
Chemistry at Uppsala University.